• A new dietary ingredient containing a special protein GMI
Introduction
What is Reishimmune™
• GMI is isolated from Reishi (Ganoderma)
It belongs to a group of Fungal Immunomodulatory Proteins (FIPs)
A new immunomodulatory protein from Ganoderma microsporum inhibits epidermal growth factor mediated migration and invasion in A549 lung cancer cells.
Process Biochemistry, 2010
GMI, a Ganoderma immunomodulatory protein, down-regulates tumor necrosis factor α-induced expression of matrix metalloproteinase 9 via NF-κB pathway in human alveolar epithelial A549 cells.
Journal of Agricultural and Food Chemistry, 2010
GMI, an immunomodulatory protein from Ganoderma microsporum, induces autophagy in non-small cell lung cancer cells.
Autophagy, 2011
Inhibition of lysosome degradation on autophagosome formation and responses to GMI, an immunomodulatory protein from Ganoderma microsporum.
British Journal of Pharmacology, 2012
GMI, an Immunomodulatory Protein from Ganoderma microsporum, Potentiates Cisplatin-Induced Apoptosis via Autophagy in Lung Cancer Cells.
Molecular Pharmaceutics, 2015
• Ongoing studies of Reishimmune™
US 7601808 B2- An immunomodulatory protein cloned from Ganoderma microsporum
TW I299735- An immunomodulatory protein cloned from Ganoderma microsporum
US 8476238 B2- Uses (Lung cancer) of an immunomodulatory protein (GMI) from Ganoderma microsporum
TW I414307- New Uses of an immunomodulatory protein (GMI) from Ganoderma microsporum
US 9018171 B2- Uses (Breast cancer) of an immunomodulatory protein (GMI) from Ganoderma microsporum
US 9161964 B2- Uses of an immunomodulatory protein (GMI) from Ganoderma microsporum
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